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PBX4 encodes a member of the pre-B cell leukemia transcription factor family. These proteins are homeobox proteins that play critical roles in embryonic development and cellular differentiation both as Hox cofactors and through Hox-independent pathways. The encoded protein contains a homeobox DNA-binding domain, but specific functions of the protein have not been determined. Alternatively spliced transcript variants have been observed for this gene.
Gene Name: | pre-B-cell leukemia homeobox 4 |
Synonyms: | PBX4, Pre-B-cell leukemia homeobox 4, Homeobox protein PBX4 |
Target Sequences: | Q9BYU1 Q9BYU1 |
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