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Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.
Gene Name: | protein kinase C and casein kinase substrate in neurons 3 |
Synonyms: | PACSIN3, Syndapin III, SDPIII, Endophilin I |
Target Sequences: | NM_016223 NP_057307.2 Q9UKS6 |
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