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Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts.
Gene Name: | leucine proline-enriched proteoglycan (leprecan) 1 |
Synonyms: | P3H1, Growth suppressor 1, Leprecan-1, GROS1, LEPRECAN, OI8, p3H1, LEPRE1, Prolyl 3-hydroxylase 1 |
Target Sequences: | NM_022356 NP_071751.3 Q32P28 |
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