Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability,
bulk quotes, proforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information requests about an LSBio product
or its application.
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution
agreements, or general business development.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Western blot (applications tested for the base form of this product only)
Unconjugated
Details
Human OTULIN / FAM105B
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated.
Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified
Applications
Western blot (1 µg/ml)
(applications tested for the base form of this product only)
Specificity and Use
Synthetic peptide located between aa238-287 of human FAM105B (Q96BN8, NP_612357). Percent identity by BLAST analysis: Human, Chimpanzee (100%).
aa238-287
Human FAM105B
Packaging
Lyophilized from PBS, 2% sucrose.
50 µl Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
OTULIN Antibody, Protein FAM105B Antibody, FAM105B Antibody
Deubiquitinase that specifically removes linear ('Met-1'-linked) polyubiquitin chains to substrates and acts as a regulator of angiogenesis and innate immune response. Associates with the LUBAC complex via direct interaction with RNF31 and counteracts its action by cleaving linear polyubiquitin chains to substrates. Required during angiogenesis, craniofacial and neuronal development by regulating the canonical Wnt signaling together with the LUBAC complex.
Western blot of Human 721_B. FAM105B antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.