Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
Western blot (0.1 - 0.2 µg/ml)
ELISA (0.15 - 0.3 µg/ml)
Neutralization (0.1 - 0.18 µg/ml)
Highly pure recombinant human Oncostatin-M.
Recognizes human Oncostatin-M.
Suitable for use in ELISA, Western Blot and Neutralization. ELISA: 0.15-0.30 ug/ml Detects human Oncostatin-M by direct ELISA (using 100 ul/well antibody solution) allows the detection of 0.2-0.4 ng/well of recombinant human Oncostatin-M. Western Blot: 0.1-0.2 ug/ml Detects recombinant human Oncostatin-M at 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. Neutralization: 0.1-0.175 ug/ml Yields one-half maximal inhibition (ND50) of the biological activity of human Oncostatin-M (10 ng/ml).
100 µl deionized water
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.