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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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OSBP Antibody (C‑Terminus) LS‑C155383
OSBP antibody LS-C155383 is an unconjugated rabbit polyclonal antibody to human OSBP. Validated for WB.
Catalog
Size
Price
LS-C155383-100
100 µl (1 mg/ml)
Unavailable

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Product Description

OSBP antibody LS-C155383 is an unconjugated rabbit polyclonal antibody to human OSBP. Validated for WB.
About OSBP
Binds cholesterol and a range of oxysterols. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylate ERK1/2, whereas 25-hydroxycholesterol causes its disassembly. Regulates cholesterol efflux by decreasing ABCA1 stability. P22059 NM_002556 NP_002547.1

OSBP Antibody, OSBP1 Antibody, Oxysterol binding protein Antibody, Oxysterol-binding protein 1 Antibody


Specifications

Target
Human OSBP
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bovine, Rabbit (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:3000)
Immunogen
OSBP antibody was raised against recombinant fragment corresponding to a region within amino acids 571 and 786 of OSBP (SwissProt P22059). Percent identity by BLAST analysis: Human (100%); Rabbit, Rat (97%); Mouse (94%); Bovine (91%).
Epitope
C-Terminus
Specificity
Human OSBP
Usage
Suggested starting dilutions are as follows: Western blot: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Presentation
PBS, pH 7, 1% BSA, 20% Glycerol, 0.01% Thimerosal
Storage
Aliquot and freeze at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Sample (30 ug of whole cell lysate) A: Jurkat B: Raji C: K562 7.5% SDS PAGE OSBP antibody diluted at 1:1000
Sample (30 ug of whole cell lysate) A: Jurkat B: Raji C: K562 7.5% SDS PAGE OSBP antibody diluted at 1:1000

Western blot

Sample (30 ug of whole cell lysate) A: Jurkat B: Raji C: K562 7.5% SDS PAGE OSBP antibody diluted at 1:1000
Sample (30 ug of whole cell lysate) A: Jurkat B: Raji C: K562 7.5% SDS PAGE OSBP antibody diluted at 1:1000

Western blot

Sample (30 ug of whole cell lysate) A: Jurkat B: Raji C: K562 7.5% SDS PAGE OSBP antibody diluted at 1:1000
Sample (30 ug of whole cell lysate) A: Jurkat B: Raji C: K562 7.5% SDS PAGE OSBP antibody diluted at 1:1000

Western blot

Sample (30 ug of whole cell lysate) A: Jurkat B: Raji C: K562 7.5% SDS PAGE OSBP antibody diluted at 1:1000
Sample (30 ug of whole cell lysate) A: Jurkat B: Raji C: K562 7.5% SDS PAGE OSBP antibody diluted at 1:1000


Requested From: 
Date Requested: 6/21/2018

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