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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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OPRM1 / Mu Opioid Receptor Antibody (aa384‑398) LS‑C17020
Mu Opioid Receptor antibody LS-C17020 is an unconjugated rabbit polyclonal antibody to Mu Opioid Receptor (OPRM1) from human, mouse, rat and other species. Validated for IF, IHC and WB.
Antibody
Catalog
Size
Price
LS-C17020-50
50 µl
$435

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Applications: Western blot, Immunoprecipitation

Product Description

Mu Opioid Receptor antibody LS-C17020 is an unconjugated rabbit polyclonal antibody to Mu Opioid Receptor (OPRM1) from human, mouse, rat and other species. Validated for IF, IHC and WB.
About OPRM1 / Mu Opioid Receptor
Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. P35372 NM_000914 CAI20458.1

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Specifications

Target
Human OPRM1 / Mu Opioid Receptor
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Horse, Pig (tested or 100% immunogen sequence identity)
Predicted
Bovine, Dog, Rabbit (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Immunofluorescence
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide corresponding to aa384-398 (NHQLENLEAETAPLP) from the C-terminus of the cloned rat mu opioid receptor-1 (bovine thyroglobulin coupled by glutaraldehyde). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Marmoset, Mouse, Rat, Horse, Pig, Opossum (100%); Bovine, Dog, Rabbit, Platypus (93%); Turkey, Chicken (80%).
Epitope
aa384-398
Specificity
Mu opioid receptor, C-terminal domain. Specificity confirmed by immunodot-blot assay. No reactivity to the N-terminus, second extracellular loop or a different segment of the carboxy tail of the mu opioid receptor. No reactivity to either the delta or kappa opioid receptor. Species cross-reactivity: Human, rat and mouse.
Usage
Suitable for use in Immunofluorescence, Immunohistochemistry, and Western Blot. Immunohistochemistry: 1:500-1:1000 (Cy3 technique); 1:6000-1:10000 (Biotin/avidin-HRP technique). Dilute antibody in PBS, 0.3% Triton X-100. Incubate 18-24 hrs at 2-8?C. Perfusion Fixation: With 500 ml 0.1 M phosphate buffer, pH 7.4, 4% paraformaldehyde for 20-30 minutes. Post Fixation: 0.1 M phosphate buffer, pH 7.4, 4% paraformaldehyde for 1.5 hours at 4?C. Sections: 10um cryostat. Note that a change in the fixation or buffering system as used in our protocol may change the configuration of the protein, and therefore, may alter the reactivity with the tissue tested. Pre-adsorption with immunogen peptide at 10 ug/ml completely eliminates labeling.
Presentation
0.09% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/17/2018

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