Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Mouse (tested or 100% immunogen sequence identity)
Rat, Bovine, Pig (at least 90% immunogen sequence identity)
Protein A purified
ICC (1:100 - 1:1000)
Western blot (1:500 - 1:3000)
Specificity and Use
NXF1 / TAP antibody was raised against recombinant fragment corresponding to a region within amino acids 449 and 619 of TAP (SwissProt Q9UBU9). Percent identity by BLAST analysis: Human (100%); Rat, Bovine (97%); Pig (96%).
NXF1 Antibody, MEX67 Antibody, Nuclear RNA export factor 1 Antibody, TAP Antibody, Tip associating protein Antibody, MRNA export factor TAP Antibody, Tip-associating protein Antibody, Tip-associated protein Antibody
NXF1 / TAP is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity.