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NTS / NT / Neurotensin is a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active.
Gene Name: | neurotensin |
Synonyms: | NTS, Neurotensin/neuromedin N, NT, NT/N, NTS1, NN, Neurotensin, NMN-125 |
Target Sequences: | NM_006183 NP_006174.1 P30990 |
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