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Purine 5-prime-nucleotidase (EC 3.1.3.5) preferentially hydrolyzes inosine 5-prime-monophosphate (IMP) and other purine nucleotides, and is allosterically activated by various compounds, including ATP. The enzyme is exclusively located in the cytoplasmic matrix of cells and may have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases.
Gene Name: | 5'-nucleotidase, cytosolic II |
Synonyms: | NT5C2, 5'-nucleotidase, cytosolic II, 5-nucleotidase, cytosolic II, Cytosolic 5-nucleotidase II, GMP, NT5CP, Purine 5 nucleotidase, NT5B, CN-II, IMP-specific 5-NT, PNT5 |
Target Sequences: | NM_012229 NP_036361.1 P49902 |
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