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Couples NMDA-sensitive glutamate receptor signaling to the nucleus and triggers long-lasting changes in the cytoarchitecture of dendrites and spine synapse processes. Part of the cAMP response element-binding protein (CREB) shut-off signaling pathway. Stimulates outgrowth of olfactory axons and migration of gonadotropin-releasing hormone (GnRH) and luteinizing-hormone-releasing hormone (LHRH) neuronal cells.
Gene Name: | NMDA receptor synaptonuclear signaling and neuronal migration factor |
Synonyms: | NSMF, HH9, Nasal embryonic LHRH factor, NELF, RP11-48C7.1 |
Target Sequences: | NM_015537 NP_056352.3 Q6X4W1 |
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