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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NRP1 / Neuropilin 1 Antibody (N‑Terminus) LS‑C9231
Neuropilin 1 antibody LS-C9231 is an unconjugated rabbit polyclonal antibody to human Neuropilin 1 (NRP1). Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C9231-100
100 µg (0.25 mg/ml)
$605

Popular NRP1 / Neuropilin 1 Products

Antibody
Species: Human
Applications: Flow Cytometry
Antibody
Species: Human
Applications: Western blot, ELISA
IHC of Neuropilin-1 (D525) pAb in paraffin-embedded human brain tissue.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay

Product Description

Neuropilin 1 antibody LS-C9231 is an unconjugated rabbit polyclonal antibody to human Neuropilin 1 (NRP1). Validated for ELISA and WB.

Specifications

Target
Human NRP1 / Neuropilin 1
Synonyms
NRP1, BDCA4, CD304, CD304 antigen, VEGF165 receptor, VEGF165R, Neuropilin 1, Neuropilin-1, Np-1, Npn-1, NRP, NP1, Transmembrane receptor
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 - 3 µg/ml)
  • ELISA (0.1 - 1 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
Synthetic peptide derived from the N-terminal region of the human neuropilin-1 (Npn-1, NRP-1) protein.
Epitope
N-Terminus
Specificity
Recognizes soluble and membrane-bound forms of human neuropilin-1. On Western blots, it identifies two bands, one at ~130-135kD representing the membrane-bound form and another at ~90kD for the soluble form. Reacts with human PC-3 prostate adenocarcinoma cell lysates. Species sequence homology: chicken and frog Npn-1. (Mouse and rat cross-reactivity is also possible).
Usage
Suitable for use in ELISA and Western Blot. ELISA: 0.1-1 ug/ml. Western Blot: 1-3 ug/ml.
Presentation
PBS, pH 7.4, 0.09% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About NRP1 / Neuropilin 1
The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. O14786 NM_003873 NP_003864.4


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Requested From: United States
Date Requested: 11/15/2018

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