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Anti-NRP1 / Neuropilin 1 Antibody (N-Terminus) LS-C9231

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Wt. Vol. Conc. Price
100 µg - 0.25 mg/ml $515
Inquire for larger quantities

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Rabbit Polyclonal (IgG) to Human NRP1 / Neuropilin 1
Human
Western blot, ELISA
Unconjugated

Details

Human NRP1 / Neuropilin 1
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified

Applications

Western blot (1 - 3 µg/ml), ELISA (0.1 - 1 µg/ml)

Specificity and Use

NRP1 / Neuropilin 1 antibody was raised against synthetic peptide derived from the N-terminal region of the human neuropilin-1 (Npn-1, NRP-1) protein.
N-Terminus
Recognizes soluble and membrane-bound forms of human neuropilin-1. On Western blots, it identifies two bands, one at ~130-135kD representing the membrane-bound form and another at ~90kD for the soluble form. Reacts with human PC-3 prostate adenocarcinoma cell lysates. Species sequence homology: chicken and frog Npn-1. (Mouse and rat cross-reactivity is also possible).
Suitable for use in ELISA and Western Blot. ELISA: 0.1-1 ug/ml. Western Blot: 1-3 ug/ml.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About NRP1 / Neuropilin 1

O14786 NM_003873 NP_003864.4

NRP1 Antibody, BDCA4 Antibody, CD304 Antibody, CD304 antigen Antibody, VEGF165 receptor Antibody, VEGF165R Antibody, Neuropilin 1 Antibody, Neuropilin-1 Antibody, Np-1 Antibody, Npn-1 Antibody, NRP Antibody, NP1 Antibody, Transmembrane receptor Antibody

The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis.

Requested From: United States
Date Requested: 9/25/2016

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