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Anti-NR1I2 / PXR Antibody (aa18-32) LS-C92290


Wt. Vol. Conc. Price
- 50 µl - $485
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular NR1I2 / PXR Antibodies

Anti-NR1I2 / PXR Antibody (C-Terminus) LS-C31660
Rabbit Polyclonal (IgG) to Human NR1I2 / PXR
Human, Monkey, Rat, Bat, Bovine, Dog, Guinea pig, Pig
Western blot
Western blot Image
Anti-NR1I2 / PXR Antibody (aa406-420) IHC-plus™ LS-B3968
Goat Polyclonal to Human NR1I2 / PXR
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human NR1I2 / PXR
Western blot


Human NR1I2 / PXR
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


Western blot (1:500 - 1:1000)

Specificity and Use

NR1I2 / PXR antibody was raised against synthetic peptide: EDTESVPGKPSVNAD, corresponding to amino acids 18-32 of Human PXR. Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey (93%); Marmoset (80%).
Recognizes human Pregnane X receptor.
Suitable for use in Western Blot. Western Blot: 1:500-1:1000. Positive control: Hep G2 nuclear extract.


PBS, 0.1% sodium azide, 0.01% Thimerosal, 0.2% gelatin
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About NR1I2 / PXR

O75469 NM_003889 NP_003880.3

NR1I2 Antibody, BXR Antibody, Orphan nuclear receptor PXR Antibody, Orphan nuclear receptor PAR1 Antibody, PARq Antibody, PRR Antibody, PXR Antibody, Pregnane X receptor Antibody, ONR1 Antibody, SAR Antibody, SXR Antibody

Pregnane X receptor (PXR), a NR1 Thyroid Hormone-Like Receptor, has been shown to mediate the effects of steroid hormones, including progesterone, glucocorticoid, and pregnenolone, and effects of xenobiotics, through the cytochrome P-450 3A gene family (CYP3A). PXR protects the body from hepatotoxicity of secondary bile acids such as lithocholic acid (LCA) by inducing expression of the hydroxylating cytochrome P450 enzyme CYP3A and promoting detoxification.

Requested From: United States
Date Requested: 10/25/2016

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