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Anti-NR1H4 / FXR Antibody (aa446-476, Rhodamine) LS-C183858

Catalog Size Price
LS-C183858-100 100 µl Unavailable

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45 NR1H4 / FXR Antibodies

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Detection of FXR in HeLa nuclear extract using LS-C2784. ECL 30 minute detection.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-NR1H4 / FXR Antibody (aa2-126) LS-C6986
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Anti-NR1H4 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B987 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-NR1H4 / FXR Antibody (aa323-372) LS-C107782
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NR1H4 antibody LS-C107782 Western blot of THP-1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-NR1H4 / FXR Antibody (aa33-82) LS-C205753
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100% Guaranteed
Rabbit Polyclonal (IgG) to Human NR1H4 / FXR
Human, Mouse, Rat
Rhodamine Conjugated


Human NR1H4 / FXR
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal



Specificity and Use

NR1H4 / FXR antibody was raised against synthetic peptide corresponding to aa446-476 of human FXR.
Human FXR.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.


May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. Sensitive to light.
For research use only.

About NR1H4 / FXR

Q96RI1 NM_005123 NP_005114.1

NR1H4 Antibody, BAR Antibody, Farnesyl x receptor Antibody, FXR Antibody, HRR1 Antibody, Farnesoid x activated receptor Antibody, Farnesoid X receptor Antibody, Farnesol receptor HRR-1 Antibody, HRR-1 Antibody, RXR-interacting protein 14 Antibody, RIP14 Antibody, Bile acid receptor Antibody, Farnesoid X nuclear receptor Antibody, Farnesoid X-activated receptor Antibody

Farnesoid X receptor (FXR), a NR1 Thyroid Hormone-Like Receptor, has been shown to affect bile-acid metabolism in the liver and intestine. FXR binds to target DNA as a heterodimer (with retinoid X receptors) and is activated by bile acids. Binding of bile acids to the RXR/FXR heterodimer in liver represses CYP7A1 expression and bile-acid production, leading to a failure to solubilize and absorb cholesterol.

Requested From: 
Date Requested: 4/19/2018

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