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Anti-NR1A2 / THRB Antibody (phospho-Ser142) LS-C199678

Catalog Size Price
LS-C199678-50 50 µl Unavailable
LS-C199678-100 100 µl Unavailable

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49 NR1A2 / THRB Antibodies

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Anti-NR1A2 / THRB Antibody (aa11-60) LS-C118594
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100% Guaranteed
Rabbit Polyclonal (IgG) to Human NR1A2 / THRB
Human, Mouse, Rat
Western blot, ELISA
Unconjugated

Details

Human NR1A2 / THRB
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (1:500 - 1:1000)
  • ELISA (1:5000)

Specificity and Use

NR1A2 / THRB antibody was raised against synthetic peptide derived from human TR-beta1 around the phosphorylation site of Ser142.
pSer142
TR-beta1 (Phospho-Ser142) Antibody detects endogenous levels of TR-beta1 only when phosphorylated at serine142.

Packaging

PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Store at -20°C.
For research use only.

About NR1A2 / THRB

P10828 NM_000461 NP_000452.2

THRB Antibody, C-erba beta2 Antibody, C-ERBA-2 Antibody, ERBA-BETA Antibody, GRTH Antibody, Oncogene ERBA2 Antibody, THRB2 Antibody, TR-BETA Antibody, THRB1 Antibody, NR1A2 Antibody, Thyroid hormone receptor beta Antibody, Trbeta1 Antibody, Trbeta2 Antibody, C-erba beta1 Antibody, C-ERBA-BETA Antibody, ERBA2 Antibody, PRTH Antibody, THR1 Antibody, Thyroid hormone receptor, beta Antibody, Trbeta Antibody

Thyroid hormone receptor beta (TR beta), a NR1 Thyroid Hormone-Like Receptor, has been shown to affect cholesterol metabolism, hearing, cone development in the eye, and hypothalamopituitary-thyroid axis function. Mice lacking the TR beta locus exhibit elevated thyroid hormone levels, profound hearing loss, impaired weight gain, abnormal bone development, and loss of thyroid-hormone induced activation of cholesterol 7 alpha-hydroxylase (CYP7A).

Western blot

Western blot
Western blot of extracts from 293 cells treated with PMA 125ng/ml 30', using TR-beta1 (Phospho-Ser142) Antibody. The lane on the right was incubated with synthetic peptide.

Requested From: 
Date Requested: 12/11/2017

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