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Anti-NPPB / BNP Antibody (clone 57H3) IHC-plus™ LS-B7942

Note: This antibody replaces LS-C51848, LS-C20943, LS-C20941, LS-C127093


Wt. Vol. Conc. Price
100 µg - 1 mg/ml Unavailable

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Mouse Monoclonal [clone 57H3] (IgG2a) to Human NPPB / BNP
IHC - Paraffin, Western blot, ELISA, Sandwich ELISA


Human NPPB / BNP
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [57H3]
Protein A purified


  • IHC - Paraffin (10 µg/ml)
  • Western blot
  • Sandwich ELISA

Specificity and Use

NPPB / BNP antibody was raised against human synthetic BNP (whole molecule) or synthetic BNP peptide 11FGRKMDRISSSS22 (for MAbs 24C5 and 26E2) conjugated with carrier protein. Percent identity by BLAST analysis: Human, Gibbon (100%); Marmoset (83%).
Human BNP and proBNP
Sandwich ELISA: works well with antibody LS-C51846 as the capture antibody.


PBS, pH 7.4, 0.1 % sodium azide.
+4°C, avoid freezing
For research use only.

About NPPB / BNP

P16860 NM_002521 NP_002512.1

NPPB Antibody, BNP Antibody, Natriuretic peptides B Antibody, Natriuretic peptide B Antibody, Natriuretic protein Antibody, Brain type natriuretic peptide Antibody

NPPB / BNP is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure.


Anti-BNP antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7942 dilution 10 ug/ml.

Requested From: 
Date Requested: 4/24/2017

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