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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NPC1L1 Antibody LS‑C131053
Antibody
NPC1L1 antibody LS-C131053 is an unconjugated rabbit polyclonal antibody to human NPC1L1. Validated for IP and WB.
Catalog
Size
Price
LS-C131053-100
100 µl
Unavailable

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Product Description

NPC1L1 antibody LS-C131053 is an unconjugated rabbit polyclonal antibody to human NPC1L1. Validated for IP and WB.
About NPC1L1
NPC1L1 is a multi-pass membrane protein. It contains a conserved N-terminal Niemann-Pick C1 (NPC1) domain and a putative sterol-sensing domain (SSD) which includes a YQRL motif functioning as a plasma membrane to trans-Golgi network transport signal in other proteins. This protein takes up free cholesterol into cells through vesicular endocytosis and plays a critical role in the absorption of intestinal cholesterol. It also has the ability to transport alpha-tocopherol (vitamin E). Q9UHC9 NM_013389 NP_037521.2

NPC1L1 Antibody, Niemann-Pick C1-like protein 1 Antibody, NPC11L1 Antibody, NPC1-like 1 Antibody


Specifications

Target
Human NPC1L1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
  • Immunoprecipitation (1:50)
Immunogen
NPC1L1 antibody was raised against synthetic peptide corresponding to central residues of human NPC1L1 (KLH).
Specificity
Recognizes endogenous levels of total human NPC1L1 protein at 140kD.
Usage
Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 1:1000. Immunoprecipitation: 1:50.
Presentation
PBS, 10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/ml BSA, 0.1% sodium azide, 50% glycerol
Storage
May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least1 year at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/17/2018

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