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Anti-NPC / NPC1 Antibody (C-Terminus, clone EPR5209) IHC-plus™ LS-B6281

Note: This antibody replaces LS-C138645


Wt. Vol. Conc. Price
- 50 µl - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular NPC / NPC1 Antibodies

Anti-NPC / NPC1 Antibody IHC-plus™ LS-B3437
Mouse Monoclonal (IgG1) to Human NPC / NPC1
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation
Immunohistochemistry Image
Anti-NPC / NPC1 Antibody (C-Terminus, clone EPR5209) IHC-plus™ LS-B6281
Rabbit Monoclonal [clone EPR5209] to Human NPC / NPC1
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Monoclonal [clone EPR5209] to Human NPC / NPC1
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot


Human NPC / NPC1
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Monoclonal [EPR5209]
Tissue culture supernatant


  • IHC - Paraffin (1:50 - 1:100)
  • ICC (1:100 - 1:250)
  • Western blot (1:1000 - 1:10000)

Specificity and Use

NPC / NPC1 antibody was raised against a synthetic peptide corresponding to residues at the C-terminus of human NPC1.
Human NPC1. Species cross-reactivity is based on WB analysis.


Tris-Glycine-NaCl or PBS, pH 7.2-7.4, 40-50% Glycerol, 0.01% sodium azide, 0.05% BSA
Store at -20°C.
For research use only.

About NPC / NPC1


NPC1 Antibody, NPC Antibody, Niemann-Pick C1 protein Antibody, Niemann-Pick disease, type C1 Antibody

Intracellular cholesterol transporter which acts in concert with NPC2 and plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment. Both NPC1 and NPC2 function as the cellular 'tag team duo' (TTD) to catalyze the mobilization of cholesterol within the multivesicular environment of the late endosome (LE) to effect egress through the limiting bilayer of the LE.


Anti-NPC1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6281 dilution 1:50.

Western blot

Western blot
Western blot analysis on (A) 3T3-L1, (B) L6, (C) HepG2, (D) THP-1, (E) 293T, (F) PC-3, (G) rat liver, and (H) rat brain lysates using LS-B6281
Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Requested From: United States
Date Requested: 10/27/2016

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