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Anti-NOD8 / NLRP10 Antibody (aa386-655, clone 11n133) LS-C184851

Catalog Size Price
LS-C184851-100 100 µg Unavailable

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100% Guaranteed
Mouse Monoclonal [clone 11n133] (IgG2b) to Human NOD8 / NLRP10
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Details

Human NOD8 / NLRP10
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [11n133]
Unconjugated
Protein A/G purified
Unmodified

Applications

Western blot (0.5 µg/ml)

Specificity and Use

NOD8 / NLRP10 antibody was raised against recombinant corresponding to aa386-655 from human Pynod expressed in E. coli (Q86W26).
aa386-655
Human Pynod. Species sequence homology: mouse and rat (50%). No cross-reactivity with recombinant human NALP1 (aa1-323), NALP1 (aa1331-1429), NALP2 (aa1-208), NALP3 (aa3-223), NALP3 (aa540-689), NALP5 (aa469-635), NOD1 (aa830-953), or NOD2 (aa230-450).

Packaging

Lyophilized from PBS, trehalose
200 µl Sterile PBS
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C.
For research use only.

About NOD8 / NLRP10

Q86W26 NP_789791.1

NLRP10 Antibody, CLR11.1 Antibody, PYNOD Antibody, NALP10 Antibody, NOD8 Antibody, PAN5 Antibody

Inhibits autoprocessing of CASP1, CASP1-dependent IL1B secretion, PYCARD aggregation and PYCARD-mediated apoptosis but not apoptosis induced by FAS or BID. Displays anti-inflammatory activity. Plays a role in adaptive immunity through control of dendritic cell-mediated transport of antigen to the lymph nodes from peripheral sites. Required for immunity against C.albicans infection.

Requested From: 
Date Requested: 8/20/2017

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