Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Specificity and Use
NMI antibody was raised against a synthetic peptide mapping to a region between residues 1 and 50 of human N-myc and STAT interactor using the numbering given in entry NP_004679.1 (GeneID 9111).
Species cross-reactivity: Human. Other species have not been tested. Reactivity with mouse NMI is likely owing to conservation of sequence between this ortholog and human NMI at the site to which the epitope maps.
Suitable for use in Western Blot and Immunoprecipitation.
NMI Antibody, Hou Antibody, N-myc and STAT interactor Antibody, N-myc-interactor Antibody, N-myc (and STAT) interactor Antibody, N-myc interactor Antibody
NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.