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Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.
Gene Name: | NME/NM23 nucleoside diphosphate kinase 6 |
Synonyms: | NME6, IPIA-ALPHA, NDK 6, NM23-H6, NDP kinase 6 |
Target Sequences: | NM_005793 NP_005784.1 O75414 |
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