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NLRP9 belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5.
Gene Name: | NLR family, pyrin domain containing 9 |
Synonyms: | NLRP9, NALP9, PAN12, CLR19.1, NOD6 |
Target Sequences: | Q7RTR0 Q7RTR0 |
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