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Anti-NLRP2 / NALP2 Antibody (aa97-115) LS-C148284

Ordering

Wt. Vol. Conc. Price
- 50 µl - $335
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular NLRP2 / NALP2 Antibodies

Anti-NLRP2 / NALP2 Antibody (C-Terminus) IHC-plus™ LS-B529
Rabbit Polyclonal to Human NLRP2 / NALP2
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-NLRP2 / NALP2 Antibody (aa1-208) LS-C73139
Sheep Polyclonal (IgG) to Human NLRP2 / NALP2
Human
Western blot
Unconjugated
Anti-NLRP2 / NALP2 Antibody (aa1-208) LS-C130967
Mouse Monoclonal (IgG2a) to Human NLRP2 / NALP2
Human
Western blot
Unconjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human NLRP2 / NALP2
Human
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Unconjugated

Details

Human NLRP2 / NALP2
Rabbit
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Antiserum
Unmodified

Applications

  • IHC - Paraffin (1:1000 - 1:5000)
  • IHC - Frozen
  • Western blot (1:1000 - 1:2000)
  • Immunoprecipitation (1:50 - 1:200)

Specificity and Use

NLRP2 / NALP2 antibody was raised against a synthetic peptide corresponding to amino acids 97-115 (LKSFNKRKPLSLGITRKER) of human NALP2, GenBank no. gi|8923473|ref|NP_060322.1. Percent identity by BLAST analysis: Human, Gorilla (100%); Monkey (95%); Gibbon (89%).
aa97-115
Detected NALP2 at approx. 110 kD in various cell line lysates and in NALP2 transfected cells (Bruey et al, 2004).

Packaging

Antiserum, 0.05% sodium azide
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
For research use only.

About NLRP2 / NALP2

Q9NX02 NM_017852 NP_060322.1

NLRP2 Antibody, CLR19.9 Antibody, PAN1 Antibody, NALP2 Antibody, NBS1 Antibody, PYPAF2 Antibody

Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.

Western blot

Western blot
Western blot of NALP2 using NALP2 antibody at 1:2000. HEK293T: mock transfected cells, HEK293T-NALP2: NALP2 transiently transfected cells; THP-1: untreated cells; THP1-LPS: cells treated with 1 ug/ml LPS for 4h. MCF-7: untreated cells.
 

Requested From: United States
Date Requested: 12/4/2016

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