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Anti-NLK Antibody (aa406-436) LS-C99910

Ordering

Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular NLK Antibodies

Anti-NLK Antibody (aa407-436, AP) LS-C264484
Rabbit Polyclonal (IgG) to Mouse NLK
Mouse
IHC, Western blot, ELISA
AP Conjugated
Anti-NLK Antibody (C-Terminus, Azide-free, HRP) LS-C280146
Rabbit Polyclonal (IgG) to Human NLK
Human
IHC, Western blot, ELISA
HRP Conjugated, Azide-free

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human NLK
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human NLK
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)

Specificity and Use

NLK antibody was raised against kLH-conjugated synthetic peptide between amino acids 406-436 from C-terminal region of human NLK.
LS-E9040 - Lyophilized - 100 µg - $145.00
aa406-436

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About NLK

Q9UBE8 NM_016231 NP_057315.3

NLK Antibody, LAK1 Antibody, Nemo-like kinase Antibody, Nmo kinase Antibody, Nemo like kinase Antibody, Protein LAK1 Antibody

Serine/threonine-protein kinase that regulates a number of transcription factors with key roles in cell fate determination. Positive effector of the non-canonical Wnt signaling pathway, acting downstream of WNT5A, MAP3K7/TAK1 and HIPK2. Activation of this pathway causes binding to and phosphorylation of the histone methyltransferase SETDB1. The NLK-SETDB1 complex subsequently interacts with PPARG, leading to methylation of PPARG target promoters at histone H3K9 and transcriptional silencing.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot
Western blot of anti-NLK antibody in A375 cell lysate. NLK (arrow) was detected using purified antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Requested From: United States
Date Requested: 12/7/2016

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