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Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses.
Gene Name: | neuroligin 1 |
Synonyms: | NLGN1, KIAA1070, Neuroligin-1, Neuroligin I, Neuroligin 1, NL1 |
Target Sequences: | NM_014932 NP_055747.1 Q8N2Q7 |
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