Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
6His fusion protein corresponding to full-length TTF-1 (Thyroid transcription factor 1, also known as Thyroid nuclear factor 1, Homeobox protein Nkx-2.1).
Recognizes TTF-1, Mr 42kD. Additional non-specific proteins also detected in longer exposures. Species cross-reactivity: Rat, mouse and human.
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Western Blot Analysis: A 1:500-1:1000 dilution of this lot detected TTF-1 in nuclear extract from H441 human lung epithelial cells. Immunoprecipitation: Has been reported by an independent laboratory to immunoprecipitate TTF-1. Immunohistochemistry: Has been reported by an independent laboratory to detect TTF-1 in 4% paraformaldehyde fixed human and mouse lung adenocarcinoma tissue.
0.05% Sodium Azide, 30% Glycerol
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
TTF-1 / Thyroid-Specific TF is a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis.