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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NKX2‑1 / Thyroid‑Specific TF Antibody LS‑C10567
Thyroid-Specific TF antibody LS-C10567 is an unconjugated mouse monoclonal antibody to Thyroid-Specific TF (NKX2-1) from human and rat. Validated for ICC, IF and IHC.
Antibody
Catalog
Size
Price
LS-C10567-1000
1000 µl
$695

Popular NKX2-1 / Thyroid-Specific TF Products

Formalin-fixed, paraffin-embedded rat lung stained with TTF1 antibody (NX2.1/690).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Flow Cytometry
Formalin-fixed, paraffin-embedded rat lung stained with peroxidase-conjugate and AEC chromogen. Note nuclear staining of alveolar epithelial cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Applications: IHC, IHC - Paraffin, Immunofluorescence
Immunofluorescence of monoclonal antibody to NKX2-1 on HeLa cell . [antibody concentration 10 ug/ml]
Species: Human
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TTF1 antibody 8G7G3/1 immunohistochemistry lung adenocarcinoma 20X This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Rat, Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence, Flow Cytometry
Anti-TTF1 / TTF-1 / NKX2-1 antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10666 dilution 1:100.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry

Product Description

NKX2-1 / Thyroid-Specific TF Antibody for ICC, IF/Immunofluorescence, IHC LS-C10567

Specifications

Target
Rat NKX2-1 / Thyroid-Specific TF
Synonyms
NKX2-1, BCH, Benign chorea, Homeobox protein Nkx-2.1, NK-2, NKX2.1, NK-2 homolog A, Thyroid transcription factor 1, NK2 homeobox 1, TTF-1, BHC, Thyroid nuclear factor 1, TITF1, NKX2A, TEBP
Host
Mouse
Reactivity
Rat, Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Ascites
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • IHC - Frozen
  • ICC
  • Immunofluorescence
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Rat TTF-1 recombinant protein.
Specificity
Reactive with human and rat. Recognizes a 40kD protein, identified as thyroid transcription factor 1 (TTF-1), selectively expressed in the lung, thyroid and diencephalon. The antigen has been localized in the nucleus.
Usage
Suitable for use in Immunofluorescence, Immunocytochemistry and Immunohistochemistry (frozen and paraffin sections, after microwave pretreatment). Tumors Specifically Detected: Useful in the classification of thyroid and lung tumors. Immunohistochemistry: 1:10-1:20. Positive control: Normal thyroid or lung.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
About NKX2-1 / Thyroid-Specific TF
TTF-1 / Thyroid-Specific TF is a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. P43699 NM_003317 NP_003308.1


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Requested From: United States
Date Requested: 10/16/2018

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