Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal to Human NFKBIA / IKB Alpha / IKBA
Human, Mouse, Rat, Bovine, Pig, Sheep
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Mouse Monoclonal (IgG1) to Human NFKBIA / IKB Alpha / IKBA
Human NFKBIA / IKB Alpha / IKBA
Human (tested or 100% immunogen sequence identity)
Specificity and Use
NFKBIA / IKB Alpha / IKBA antibody was raised against synthetic peptide corresponding to the caspase-3 mediated cleavage site of IkBa.
Recognizes human RBM25.
Suitable for use in Western Blot.
PBS, pH 7.2, 0.02% sodium azide
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C.
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.