Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone RT97] (IgG1) to Human NEFH / NF-H
Human NEFH / NF-H
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [RT97]
Specificity and Use
Reacts with Avian, Human, Mammalian, Rat, Chicken, Porcine and Reptilian. Also recognizes the following tumors: phaeochromocytoma, paraganglioma, ganglioneuroblastoma and other tumors of neuronal origin.
PBS, 10 mM sodium azide, 1 mg/ml BSA
Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.