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Anti-NCK1 / NCK Antibody (Gly300) LS-C37473

Catalog Size Price
LS-C37473-100 100 µl Unavailable

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100% Guaranteed
Rabbit Monoclonal (IgG) to Human NCK1 / NCK
Human, Monkey, Mouse, Rat
Western blot, Immunoprecipitation, ELISA
Unconjugated

Details

Human NCK1 / NCK
Rabbit
Human, Monkey, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Monoclonal
Unconjugated
Tissue culture supernatant
Unmodified

Applications

  • Western blot
  • Immunoprecipitation
  • ELISA

Specificity and Use

NCK1 / NCK antibody was raised against synthetic peptide (KLH-coupled) corresponding to residues surrounding Gly300 of human NCK1.
Gly300
Detects the endogenous levels of total NCK1 protein. Based on homology it may also recognize NCK2. Species cross-reactivity: Human, monkey, mouse and rat.
Suitable for use in ELISA, Western Blot and Immunoprecipitation. Western blot 1: Immunoprecipitation 1:.

Packaging

10 mM HEPES, pH 7.5, 150 mM sodium chloride, 100 ug/ml BSA, 50% glycerol, less than 0.02% sodium azide.
For research use only.

About NCK1 / NCK

P16333 NM_006153 NP_006144.1

NCK1 Antibody, Cytoplasmic protein nck Antibody, Cytoplasmic protein NCK1 Antibody, NCK adaptor protein 1 Antibody, Nck-1 Antibody, NCKalpha Antibody, Melanoma NCK protein Antibody, NCK Antibody, NCK tyrosine kinase Antibody

Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.

Requested From: 
Date Requested: 10/18/2017

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