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Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.
Gene Name: | N-acetyltransferase 10 (GCN5-related) |
Synonyms: | NAT10, ALP, HALP, KIAA1709, N-acetyltransferase 10, NET43 |
Target Sequences: | NM_024662 NP_078938.2 Q9H0A0 |
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