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Anti-MYOC / Myocilin Antibody (aa69-85) IHC-plus™ LS-B2262

Note: This antibody replaces LS-C3222

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MYOC / Myocilin Antibodies

Anti-MYOC / Myocilin Antibody (aa69-85) IHC-plus™ LS-B2262
Rabbit Polyclonal to Human MYOC / Myocilin
Human
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-MYOC / Myocilin Antibody (clone 4F8) IHC-plus™ LS-B4382
Mouse Monoclonal [clone 4F8] (IgG1,k) to Human MYOC / Myocilin
Human
IHC - Paraffin, Western blot, ELISA, RNA interference
Unconjugated
Immunohistochemistry Image
Anti-MYOC / Myocilin Antibody (aa224-471, FITC) LS-C305210
Rabbit Polyclonal (IgG) to Human MYOC / Myocilin
Human
Western blot, ELISA
FITC Conjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human MYOC / Myocilin
Human
IHC - Paraffin, ELISA
Unconjugated

Details

Human MYOC / Myocilin
Rabbit
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • ELISA (1:1000)

Specificity and Use

MYOC / Myocilin antibody was raised against synthetic peptide from human MYOC. Percent identity by BLAST analysis: Human, Gibbon, Marmoset (100%); Monkey (94%).
aa69-85
KLH conjugated synthetic peptide comprising amino acids 69 - 85 [SVIHNLQRDSSTQRLDL] of the human myocilin (MYOC) protein.
Immunohistochemistry: LS-B2262 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2262 was determined to be 5 ug/ml.

Packaging

PBS, 0.09% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About MYOC / Myocilin

Q99972 NM_000261 NP_000252.1

MYOC Antibody, GLC1A Antibody, JOAG Antibody, JOAG1 Antibody, Myocilin Antibody, TIGR Antibody, GPOA Antibody

Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction.

Immunohistochemistry

Immunohistochemistry
Anti-MYOC antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2262 concentration 5 ug/ml.
 

Requested From: United States
Date Requested: 12/7/2016

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