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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MVK Antibody (clone 2C5) LS‑C133916 Best Seller
Note: This antibody replaces LS-C122167
MVK antibody LS-C133916 is an unconjugated mouse monoclonal antibody to human MVK. Validated for ELISA, IHC and WB.
Catalog
Size
Price
LS-C133916-100
100 µg
Unavailable

Popular MVK Products

IHC of MVK (N175) pAb in paraffin-embedded human brain tissue.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Immunohistochemical analysis of MVK staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Species: Human, Monkey
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Western blot of MVK antibody
Species: Human, Monkey
Applications: IHC, Immunofluorescence, Western blot, ELISA
Immunohistochemistry of Human esophagus cancer using MVK Polyclonal Antibody at dilution of 1:40.
Species: Human, Mouse, Rat
Applications: IHC, Western blot, ELISA

Product Description

MVK antibody LS-C133916 is an unconjugated mouse monoclonal antibody to human MVK. Validated for ELISA, IHC and WB.
About MVK
MVK is the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Q03426 NM_000431 NP_000422.1

MVK Antibody, Mevalonate kinase Antibody, Mevalonate kinase 1 Antibody, MK Antibody, LRBP Antibody, MVLK Antibody, POROK3 Antibody


Specifications

Target
Human MVK
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a,k Monoclonal [2C5]
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (3 µg/ml)
  • Western blot
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
MVK antibody was raised against mVK (AAH16140, 297 a.a. ~ 397 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human MVK
Usage
Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western Blot: Transfected lysate, Recombinant protein.
Presentation
PBS, pH 7.4
Storage
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Immunoperoxidase of monoclonal antibody to MVK on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml]
Immunoperoxidase of monoclonal antibody to MVK on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml]

Western blot

Western blot of MVK expression in transfected 293T cell line by MVK monoclonal antibody (M02), clone 2C5.
Western blot of MVK expression in transfected 293T cell line by MVK monoclonal antibody (M02), clone 2C5.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged MVK is approximately 3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged MVK is approximately 3 ng/ml as a capture antibody.

Immunohistochemistry

Immunoperoxidase of monoclonal antibody to MVK on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml]
Immunoperoxidase of monoclonal antibody to MVK on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml]

Western blot

Western blot of MVK expression in transfected 293T cell line by MVK monoclonal antibody (M02), clone 2C5.
Western blot of MVK expression in transfected 293T cell line by MVK monoclonal antibody (M02), clone 2C5.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged MVK is approximately 3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged MVK is approximately 3 ng/ml as a capture antibody.

Immunohistochemistry

Immunoperoxidase of monoclonal antibody to MVK on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml]
Immunoperoxidase of monoclonal antibody to MVK on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml]

Western blot

Western blot of MVK expression in transfected 293T cell line by MVK monoclonal antibody (M02), clone 2C5.
Western blot of MVK expression in transfected 293T cell line by MVK monoclonal antibody (M02), clone 2C5.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged MVK is approximately 3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged MVK is approximately 3 ng/ml as a capture antibody.

Immunohistochemistry

Immunoperoxidase of monoclonal antibody to MVK on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml]
Immunoperoxidase of monoclonal antibody to MVK on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml]

Western blot

Western blot of MVK expression in transfected 293T cell line by MVK monoclonal antibody (M02), clone 2C5.
Western blot of MVK expression in transfected 293T cell line by MVK monoclonal antibody (M02), clone 2C5.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged MVK is approximately 3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged MVK is approximately 3 ng/ml as a capture antibody.


Requested From: 
Date Requested: 6/22/2018

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