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Anti-MURF1 / IRF Antibody (aa251-300) LS-C110780

Catalog Size Price
LS-C110780-50 50 µg Unavailable

Related Products

16 MURF1 / IRF Antibodies

Most Popular MURF1 / IRF Antibodies

Anti-MURF1 / IRF Antibody (aa247-261) IHC-plus™ LS-B1750
Goat Polyclonal to Human MURF1 / IRF
Human, Monkey
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-MURF1 / IRF Antibody (aa2-14) IHC-plus™ LS-B1751
Goat Polyclonal to Human MURF1 / IRF
Human, Monkey, Bovine, Dog, Horse
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-MURF1 / IRF Antibody (aa1-44) LS-C186154
Rabbit Polyclonal to Human MURF1 / IRF
Human, Bovine, Pig
IHC - Paraffin, ICC, Western blot
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Immunohistochemistry Image
Anti-MURF1 / IRF Antibody LS-C332362
Rabbit Polyclonal (IgG) to Human MURF1 / IRF
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot
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Immunohistochemistry Image
Anti-MURF1 / IRF Antibody LS-C402695
Rabbit Polyclonal (IgG) to Human MURF1 / IRF
Human, Mouse
IHC, Western blot, ELISA
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Immunohistochemistry Image

100% Guaranteed
Rabbit Polyclonal to Human MURF1 / IRF
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human MURF1 / IRF
Rabbit
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

MURF1 / IRF antibody was raised against synthetic peptide located between aa251-300 of human TRIM63 (Q969Q1, NP_115977). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Bat, Rabbit, Horse, Pig, Guinea pig (100%); Elephant, Opossum, Platypus (92%).
LS-E15953 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C110780. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa251-300
Human TRIM63 / MURF1
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Packaging

Lyophilized from PBS with 2% sucrose
Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About MURF1 / IRF

Q969Q1 NM_032588 NP_115977.2

TRIM63 Antibody, Iris RING finger protein Antibody, MURF-1 Antibody, MURF1 Antibody, MuRF2 Antibody, IRF Antibody, RING finger protein 28 Antibody, RNF28 Antibody, Tripartite motif-containing 63 Antibody, Tripartite motif containing 63 Antibody, SMRZ Antibody

E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins.

Western blot

Western blot
TRIM63 / MURF1 antibody LS-C110780 Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 10/22/2017

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