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Anti-MUC4 Antibody (clone 1G8) LS-C9121

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $530
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
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Mouse Monoclonal [clone 1G8] (IgG1) to Rat MUC4
Rat, Human, Mouse
IHC, Western blot, ELISA
Unconjugated

Details

Rat MUC4
Mouse
Rat, Human, Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [1G8]
Protein A purified

Applications

IHC (2 - 5 µg/ml), Western blot (1 - 2 µg/ml), ELISA (2 - 5 µg/ml)

Specificity and Use

MUC4 antibody was raised against rat ASGP-2.
Recognizes an epitope on the ASGP-2 subunit, which is one of the main subunits that comprise the MUC4 glycoprotein complex. Reactivity is confirmed with ASGP-2 transfected COS-7 cells and rat microvilli isolated from ascites cells of 13762 rat mammary adenocarcinoma. Species cross-reactivity: Human and mouse.
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Western Blot: 1-2 ug/ml. ELISA: <0.1 ug/ml. Immunohistochemistry: 2-5 ug/ml Heat-induced epitope retrieval (Citrate buffer, pH 6.0).

Packaging

PBS, pH 7.4, 0.1% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About MUC4

NM_018406

MUC4 Antibody, ASGP Antibody, HSA276359 Antibody, Mucin-4 Antibody, Testis mucin Antibody, Tracheobronchial mucin Antibody, Ascites sialoglycoprotein Antibody, MUC-4 Antibody, Mucin 4, tracheobronchial Antibody

May play a role in tumor progression. Ability to promote tumor growth may be mainly due to repression of apoptosis as opposed to proliferation. Has anti-adhesive properties. Seems to alter cellular behavior through both anti-adhesive effects on cell-cell and cell-extracellular matrix interactions and in its ability to act as an intramembrane ligand for ERBB2. Plays an important role in cell proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2.

Requested From: United States
Date Requested: 9/24/2016

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