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Anti-MTHFR Antibody (aa685-697) IHC-plus™ LS-B9203

Note: This antibody replaces LS-C112880

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MTHFR Antibodies

Anti-MTHFR Antibody (aa369-383) LS-C154913
Goat Polyclonal to Human MTHFR
Human, Monkey, Bovine, Dog, Rabbit
Western blot, ELISA
Unconjugated
Western blot Image
Anti-MTHFR Antibody (aa266-292) LS-C157974
Rabbit Polyclonal to Human MTHFR
Human
Western blot
Unconjugated
Western blot Image
Anti-MTHFR Antibody (Internal) LS-C352540
Rabbit Polyclonal to Human MTHFR
Human, Monkey, Mouse
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human MTHFR
Human
IHC - Paraffin, ELISA
Unconjugated

Details

Human MTHFR
Goat
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (3.75 µg/ml)
  • ELISA (1:16000)

Specificity and Use

MTHFR antibody was raised against synthetic peptide C-NRPTQNARETEAP from the C-terminus of human MTHFR (NP_005948.3). Percent identity by BLAST analysis: Human, Gorilla (100%); Monkey (92%).
LS-E27065 - Lyophilized - 100 µg - $145.00
aa685-697
Human MTHFR.
Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Preliminary experiments gave an approx 28kDa band in Human Brain (Cerebellum), Skeletal Muscle and Placenta lysates after 0.2 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 74.6kDa according to NP_005948.3. The 28kDa band was successfully blocked by incubation with the immunizing peptide.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About MTHFR

P42898 NM_005957 NP_005948.3

MTHFR Antibody

MTHFR catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

Immunohistochemistry

Immunohistochemistry
Anti-MTHFR antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
 

Requested From: United States
Date Requested: 12/3/2016

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