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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MTA1 Antibody (Internal) IHC‑plus™ LS‑B4428
Note: This antibody replaces LS-C34626
MTA1 antibody LS-B4428 is an unconjugated goat polyclonal antibody to human MTA1. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B4428-50
50 µg
Unavailable

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Antibody
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Product Description

MTA1 antibody LS-B4428 is an unconjugated goat polyclonal antibody to human MTA1. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues.
About MTA1
Transcriptional coregulator which can act as both a transcriptional corepressor and coactivator. As a part of the histone-deacetylase multiprotein complex (NuRD), regulates transcription of its targets by modifying the acetylation status of the target chromatin and cofactor accessibility to the target DNA. In conjunction with other components of NuRD, acts as a transcriptional corepressor of BRCA1, ESR1, TFF1 and CDKN1A. Q13330 NM_004689 NP_004680.2

MTA1 Antibody, Metastasis associated 1 Antibody


Specifications

Target
Human MTA1
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (3.75 µg/ml)
  • Western blot (0.03 - 0.1 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:16000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
MTA1 antibody was raised against synthetic peptide C-PGDVFYMPKE from an internal region (near the C-terminus) of human MTA1 (NP_004680.1). Percent identity by BLAST analysis: Penicillium, Trichomonas, Coccidioides (80%).
Blocking Peptide
LS-E25242 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B4428. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Internal
Specificity
Human MTA1.
Usage
Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Approx 75 kDa band observed in Human Placenta lysates (calculated MW of 80.8 kDa according to NP_004680.1). Recommended concentration: 0.03-0.1 ug/ml.
Presentation
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-MTA1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.
Anti-MTA1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.

Immunohistochemistry

Anti-MTA1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.
Anti-MTA1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.

Western blot

Staining (0.03?g/ml) of Human Placenta lysate (RIPA buffer, 35?g total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.
Staining (0.03?g/ml) of Human Placenta lysate (RIPA buffer, 35?g total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

Western blot

MTA1 antibody staining (0.03 ug/ml) of Human Placenta lysate (RIPA buffer, 35g total protein per lane). Primary incubated for 1 hour. Detected using chemiluminescence.
MTA1 antibody staining (0.03 ug/ml) of Human Placenta lysate (RIPA buffer, 35g total protein per lane). Primary incubated for 1 hour. Detected using chemiluminescence.

Immunohistochemistry

Anti-MTA1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.
Anti-MTA1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.

Immunohistochemistry

Anti-MTA1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.
Anti-MTA1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.

Western blot

Staining (0.03?g/ml) of Human Placenta lysate (RIPA buffer, 35?g total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.
Staining (0.03?g/ml) of Human Placenta lysate (RIPA buffer, 35?g total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

Western blot

MTA1 antibody staining (0.03 ug/ml) of Human Placenta lysate (RIPA buffer, 35g total protein per lane). Primary incubated for 1 hour. Detected using chemiluminescence.
MTA1 antibody staining (0.03 ug/ml) of Human Placenta lysate (RIPA buffer, 35g total protein per lane). Primary incubated for 1 hour. Detected using chemiluminescence.

Immunohistochemistry

Anti-MTA1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.
Anti-MTA1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.

Immunohistochemistry

Anti-MTA1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.
Anti-MTA1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.

Western blot

Staining (0.03?g/ml) of Human Placenta lysate (RIPA buffer, 35?g total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.
Staining (0.03?g/ml) of Human Placenta lysate (RIPA buffer, 35?g total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

Western blot

MTA1 antibody staining (0.03 ug/ml) of Human Placenta lysate (RIPA buffer, 35g total protein per lane). Primary incubated for 1 hour. Detected using chemiluminescence.
MTA1 antibody staining (0.03 ug/ml) of Human Placenta lysate (RIPA buffer, 35g total protein per lane). Primary incubated for 1 hour. Detected using chemiluminescence.

Immunohistochemistry

Anti-MTA1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.
Anti-MTA1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.

Immunohistochemistry

Anti-MTA1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.
Anti-MTA1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4428 concentration 3.75 ug/ml.

Western blot

Staining (0.03?g/ml) of Human Placenta lysate (RIPA buffer, 35?g total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.
Staining (0.03?g/ml) of Human Placenta lysate (RIPA buffer, 35?g total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

Western blot

MTA1 antibody staining (0.03 ug/ml) of Human Placenta lysate (RIPA buffer, 35g total protein per lane). Primary incubated for 1 hour. Detected using chemiluminescence.
MTA1 antibody staining (0.03 ug/ml) of Human Placenta lysate (RIPA buffer, 35g total protein per lane). Primary incubated for 1 hour. Detected using chemiluminescence.


Requested From: 
Date Requested: 6/22/2018

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