Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone 10B1015] (IgG2b) to Mouse MSR1 / CD204
Mouse, Channel catfish, Porcine
Goat Polyclonal (IgG) to Human MSR1 / CD204
IHC, Western blot, ELISA
Human MSR1 / CD204
Human (tested or 100% immunogen sequence identity)
Specificity and Use
MSR1 / CD204 antibody was raised against synthetic peptide corresponding to aa 325-342 of human MSR1. MSR1 is also known as scavenger receptor A. Epitope: aa 325-342.
Recognizes the 75kD membrane glycoprotein human macrophage scavenger receptor (MSR) type 1. MSR1 has been shown to be expressed on microglia and Mato cells of the brain but not astrocytes or neurons. Species cross-reactivity: Cross-reacts with Human.
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
MSR1 / CD204 is the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense.