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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MSH2 Antibody LS‑C9098
MSH2 antibody LS-C9098 is an unconjugated mouse monoclonal antibody to human MSH2. Validated for IHC.
Antibody
Catalog
Size
Price
LS-C9098-500
500 µl
Unavailable

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Product Description

MSH2 antibody LS-C9098 is an unconjugated mouse monoclonal antibody to human MSH2. Validated for IHC.
About MSH2
Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. P43246 NM_000251 NP_000242.1

MSH2 Antibody, COCA1 Antibody, FCC1 Antibody, HNPCC Antibody, HNPCC1 Antibody, MutS protein homolog 2 Antibody, HMSH2 Antibody, LCFS2 Antibody


Specifications

Target
Human MSH2
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
MSH2 antibody was raised against recombinant human MSH2 protein. Cellular Localization: Nuclear.
Specificity
Recognizes human MSH2.
Usage
Suitable for use in Immunohistochemistry. Immunohistochemistry: (formalin/paraffin): 1:5 for 60 min at RT) requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Positive control: Tonsil.
Presentation
0.09% sodium azide.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 7/20/2018

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