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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MSH2 Antibody LS‑C9095
MSH2 antibody LS-C9095 is an unconjugated mouse monoclonal antibody to human MSH2. Validated for IHC.
Antibody
Catalog
Size
Price
LS-C9095-200
200 µl
$710

Popular MSH2 Products

IHC of paraffin-embedded human rectum carcinoma tissue showing nuclear and cytoplasmic localization using MSH2 antibody with DAB staining.
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, ELISA
IHC of MSH2 on FFPE Colon Carcinoma tissue.
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen
Anti-MSH2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: ICC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
IHC using MSH2 Antibody (1B3=3A2B8C)
Species: Human, Primate
Applications: IHC, ICC, Immunofluorescence, Western blot

Product Description

MSH2 antibody LS-C9095 is an unconjugated mouse monoclonal antibody to human MSH2. Validated for IHC.

Specifications

Target
Human MSH2
Synonyms
MSH2, COCA1, FCC1, HNPCC, HNPCC1, MutS protein homolog 2, HMSH2, LCFS2
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • IHC - Frozen
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
MSH2 antibody was raised against c6112702.
Specificity
Recognizes human MSH2.
Usage
Applications: Suitable for use in Immunohistochemistry. Immunohistochemistry: frozen and formalin-fixed, paraffin-embedded tissues. Positive control: Normal colon or breast carcinoma.
Presentation
PBS, pH 7.2, 0.1% Sodium Azide, 1% BSA
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
About MSH2
Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. P43246 NM_000251 NP_000242.1


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Requested From: United States
Date Requested: 11/15/2018

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