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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MRGBP Antibody (aa59‑73) LS‑C186555
MRGBP antibody LS-C186555 is an unconjugated goat polyclonal antibody to MRGBP from human, bovine, dog and other species. Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C186555-100
100 µg (0.5 mg/ml)
Unavailable

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Product Description

MRGBP antibody LS-C186555 is an unconjugated goat polyclonal antibody to MRGBP from human, bovine, dog and other species. Validated for Peptide-ELISA and WB.
About MRGBP
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Q9NV56 NM_018270 NP_060740.1

MRGBP Antibody, C20orf20 Antibody, Eaf7 Antibody, MRG/MORF4L binding protein Antibody, MRG15BP Antibody, URCC4 Antibody


Specifications

Target
Human MRGBP
Host
Goat
Reactivity
Human, Bovine, Dog, Guinea pig, Hamster, Horse (tested or 100% immunogen sequence identity)
Predicted
Xenopus, Zebrafish (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.3 - 1 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:32000)
Immunogen
MRGBP antibody was raised against synthetic peptide CIRDKFSQNIGRQVP from an internal region of human MRGBP / C20orf20 (NP_060740.1). Percent identity by BLAST analysis: Hamster, Elephant, Panda, Bovine, Dog, Cat, Horse, Guinea pig (100%); Xenopus, Salmon, Stickleback, Medaka, Pufferfish, Zebrafish (93%); Opossum, Turkey, Zebra finch, Chicken, Platypus, Lizard (87%).
Blocking Peptide
LS-E27998 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C186555. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa59-73
Specificity
Human MRGBP
Usage
Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Approx 21kD band observed in Human Testis lysates (calculated MW of 22.4kD according to NP_060740.1). Recommended concentration: 0.3-1 ug/ml.
Presentation
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

MRGBP antibody (0.3 ug/ml) staining of Human Testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
MRGBP antibody (0.3 ug/ml) staining of Human Testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

MRGBP antibody (0.3 ug/ml) staining of Human Testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
MRGBP antibody (0.3 ug/ml) staining of Human Testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

MRGBP antibody (0.3 ug/ml) staining of Human Testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
MRGBP antibody (0.3 ug/ml) staining of Human Testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

MRGBP antibody (0.3 ug/ml) staining of Human Testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
MRGBP antibody (0.3 ug/ml) staining of Human Testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


Requested From: 
Date Requested: 6/23/2018

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