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Anti-MMP7 Antibody (C-Terminus) IHC-plus™ LS-B1237

Note: This antibody replaces LS-C33117

Ordering

Wt. Vol. Conc. Price
50 µg 250 µl 0.2 mg/ml $395

LSBio (Direct) LSBio (Direct)
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MMP7 Antibody LS-B1237 Images

[click image for a larger image and more details]
Immunohistochemistry
Anti-MMP7 antibody IHC of human spleen.

100% Guaranteed 100% Guaranteed Publications Publications (1)
Rabbit Polyclonal to Human MMP7
Human, Mouse, Rat
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated

Details

Human MMP7
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (10 µg/ml), Western blot (0.5 - 2 µg/ml), Immunoprecipitation (2 - 5 ng/10E6 cells)

Specificity and Use

MMP7 antibody was raised against synthetic peptide from human MMP7.
C-Terminus
Peptide from the C-terminus of human MMP7
Immunohistochemistry: LS-B1237 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1237 was determined to be 10 ug/ml.

Packaging

PBS, pH 7.4, 0.1% BSA, 0.05% sodium azide.
Store at 2-8°C for up to 1 year. Avoid repeated freeze-thaw cycles.
For research use only.

Publications (1)

1
Regulated expression of matrix metalloproteinases, inflammatory mediators, and endometrial matrix remodeling by 17beta-estradiol in the immature rat uterus. Russo LA, Peano BJ, Trivedi SP, Cavalcanto TD, Olenchock BA, Caruso JA, Smolock AR, Vishnevsky O, Gardner RM. Reproductive biology and endocrinology : RB&E. 2009 7:124. (WB; Rat) [PubMed:19889233] [PMC:PMC2776020]

About MMP7

P09237 NM_002423 NP_002414.1

MMP7 Antibody, Matrilysin Antibody, Matrin Antibody, MMP-7 Antibody, MPSL1 Antibody, PUMP-1 Antibody, Pump-1 protease Antibody, MPMM Antibody, Uterine matrilysin Antibody, Punctuated metalloproteinase 1 Antibody, Matrix metalloproteinase-7 Antibody, PUMP1 Antibody, Uterine metalloproteinase Antibody

MMP7 is a Metallopeptidase M10A type protease. MMP-7 (Matrilysin) is constitutively produced by exocrine epithelial cells through out the body. It is capable of degrading casein, fibronectin, gelatins of types 1, III, IV, and V, in addition to activating procollagenase. It has been shown to play a key role in invasion by carcinomas.

Immunohistochemistry

Immunohistochemistry
Anti-MMP7 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1237 concentration 10 ug/ml.
 

Requested From: United States
Date Requested: 5/29/2015

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