Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone F36P1B4] (IgG1,k) to Human MMP3
Western blot, ELISA
Human, Monkey (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [F36P1B4]
IHC - Paraffin
Specificity and Use
MMP3 antibody was raised against synthetic peptide from human MMP3. Percent identity by BLAST analysis: Human, Marmoset (100%); Gibbon (91%); Monkey, Rat, Rabbit, Grape, Arabidopsis, Castor bean, Nectri, Fusarium (82%).
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.