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Anti-MMP13 Antibody LS-C8852

Ordering

Wt. Vol. Conc. Price
- 500 µl 0.2 mg/ml $530
Inquire for larger quantities

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Mouse Monoclonal (IgG1,k) to Rat MMP13
Rat, Mouse
Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated

Details

Rat MMP13
Mouse
Rat, Mouse (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal
Protein G purified

Applications

Immunofluorescence, Western blot (1 µg/ml), Immunoprecipitation

Specificity and Use

MMP13 antibody was raised against rat MMP-13 from BC-1 cells. MW of Antigen: 48kD (active form), 60kD (pro form). Cellular Localization: Cytoplasmic.
Recognizes rat pro (latent) and active forms of matrix metalloproteinase-13 (MMP-13; also known as collagenase-3). Does not react with human. Species cross-reactivity: mouse.
Suitable for use in Immunofluorescence, Immunoprecipitation and Western Blot. Western Blot: 1 ug/ml for 2hrs at RT. Immunoprecipitation (Native Verified): 2 ug/mg protein lysate (Use protein G). Positive control: Conditioned, serum-free medium from TPA-treated rat keratinocyte CCL-4 cells.

Packaging

Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.1% sodium azide.
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About MMP13

P45452 NM_002427 NP_002418.1

MMP13 Antibody, Collagenase 3 Antibody, Matrix metalloproteinase-13 Antibody, Interstitial collagenase Antibody, MANDP1 Antibody, MMP-13 Antibody, CLG3 Antibody

Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF.

Requested From: United States
Date Requested: 9/25/2016

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