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Anti-MLANA / Melan-A Antibody LS-C72413


Wt. Vol. Conc. Price
- 250 µl - $575
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular MLANA / Melan-A Antibodies

Anti-MLANA / Melan-A Antibody (C-Terminus) IHC-plus™ LS-B2665
Rabbit Polyclonal to Human MLANA / Melan-A
IHC - Paraffin
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG,k) to Human MLANA / Melan-A
IHC - Paraffin, IHC - Frozen


Human MLANA / Melan-A
Human (tested or 100% immunogen sequence identity)
IgG,k Monoclonal
Tissue culture supernatant


  • IHC - Paraffin
  • IHC - Frozen

Specificity and Use

MLANA / Melan-A antibody was raised against hMB45 - Pigmented melanoma metastases from LNMART-1 - Recombinant human MART-1 protein Tyrosinase - Recombinant tyrosinase protein.
Reacts with a neuraminidase-sensitive oligosaccharide side chain of a glycoconjugate present in immature melanosomes. The clone specific-reactive antigen is present in cutaneous melanocytes, prenatal and infantile retinal pigmented epithelium and melanoma cells and is thought to be oncofetal in nature. This antibody has been shown to label the majority of melanomas. MART-1 recognizes a protein of 18kD, identified at MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. Melan-A is a useful addition to melanoma panels as it is apparently specific for melanocytic lesions. Studies have also shown that MART-1 is more sensitive than HMB45 when labeling metastatic melanomas. Tyrosinase is a key enzyme involved in the initial stages of melanin biosynthesis. Studies have shown Tyrosinase to be a more sensitive marker when compared to HMB45 and MART-1. It has also shown to label a higher percentage of desmoplastic melanomas than HMB45. Species cross-reactivity: Cross-reacts with Human.
Suitable for use in Immunohistochemistry (Fr) (paraffin-embedded sections). Positive control: Metastatic melanoma in lymph node.


Proprietary, not sodium azide or Thimerosal. PBS, Tissue Culture Supernatant.
For research use only.

About MLANA / Melan-A

Q16655 NM_005511 NP_005502.1

MLANA Antibody, Antigen LB39-AA Antibody, Antigen SK29-AA Antibody, Melan-A Antibody, Protein Melan-A Antibody, MART-1 Antibody, MART1 Antibody

Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.

Requested From: United States
Date Requested: 10/28/2016

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