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Catalog Number Size Price
LS-C391943-20 20 µg (0.2 mg/ml) $371 
LS-C391943-100 100 µg (0.2 mg/ml) $574 
MITF Antibody - IHC testing of FFPE human melanoma with MITF antibody (clone MPAF3).  This image was taken for the unmodified form of this product. Other forms have not been tested.

Monoclonal Mouse anti‑Human MITF Antibody (clone MPAF3, IHC, IF) LS‑C391943

Monoclonal Mouse anti‑Human MITF Antibody (clone MPAF3, IHC, IF) LS‑C391943

Antibody:
MITF Mouse anti-Human Monoclonal (MPAF3) Antibody
Application:
IHC, IHC-P, IF
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$371
LS-C391943-20
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
MITF Mouse anti-Human Monoclonal (MPAF3) Antibody
Application:
IHC, IHC-P, IF
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
MITF antibody LS-C391943 is an unconjugated mouse monoclonal antibody to human MITF. Validated for IF and IHC.
Target
Human MITF
Synonyms
MITF | BHLHe32 | CMM8 | MI | Waardenburg syndrome, type 2A | WS2 | WS2A
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Non-Reactivity
Mouse, Rat
Clonality
IgG1,k Monoclonal
Clone
MPAF3
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified. Also available Azide-free, BSA-free, Ready-to-Use.
Immunogen
Recombinant Full-length Human Protein.
Specificity
Human MITF
Applications
  • IHC
  • IHC - Paraffin (1 - 2 µg/ml)
  • Immunofluorescence (1 - 2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
MITF (microphthalmia transcription factor) is a transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. [UniProt] Titering of the MITF antibody may be required for optimal performance. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
Presentation
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About MITF
O75030 NM_000248 NP_000239.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/26/2024