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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Mineralocorticoid Receptor Antibody (aa654‑683) LS‑C158423
Mineralocorticoid Receptor antibody LS-C158423 is an unconjugated rabbit polyclonal antibody to human Mineralocorticoid Receptor. Validated for WB.
Catalog
Size
Price
LS-C158423-400
400 µl
Unavailable

Popular Mineralocorticoid Receptor Products

NR3C2 antibody LS-C40521 IHC of formalin-fixed, paraffin-embedded human Kidney. Positive label: Epithelial cells of renal tubule indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Bovine, Horse
Applications: IHC, IHC - Paraffin, Western blot
Anti-NR3C2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3162 dilution 1:50.
Species: Human, Rat, Rabbit, Chicken
Applications: IHC, IHC - Paraffin, Western blot
NR3C2 antibody LS-C107485 Western blot of HT1080 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat, Bovine, Horse, Pig
Applications: Western blot
NR3C2 antibody LS-C112346 Western blot of PANC1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Horse, Chicken
Applications: Western blot
Antibody
Species: Human
Applications: IHC, Immunofluorescence, Western blot, Immunoprecipitation, ELISA

Product Description

Mineralocorticoid Receptor antibody LS-C158423 is an unconjugated rabbit polyclonal antibody to human Mineralocorticoid Receptor. Validated for WB.
About Mineralocorticoid Receptor
The mineralocorticoid receptor (MR), a NR3 Steroid Receptor, has been shown to affect hypothalamic-pituitary-adrenocortical axis activity in the brain, sodium and potassium transport, and stress-related psychiatric diseases such as major depression. MR binds aldosterone and glucocorticoid with equal affinity, and the binding specificity is regulated by the enzyme 11beta-hydroxysteroid-dehydrogenase type II. P08235 NM_000901 NP_000892.2

NR3C2 Antibody, MCR Antibody, Mineralocorticoid receptor Antibody, NR3C2VIT Antibody, Aldosterone receptor Antibody, Mineralocorticoid receptor 1 Antibody, MLR Antibody, MR Antibody


Specifications

Target
Human Mineralocorticoid Receptor
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Xenopus (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Blocking Peptide
LS-E4822 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C158423. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa654-683
Specificity
This NR3C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-683 amino acids from the Central region of human NR3C2.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

NR3C2 Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The NR3C2 antibody detected the NR3C2 protein (arrow).
NR3C2 Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The NR3C2 antibody detected the NR3C2 protein (arrow).

Western blot

NR3C2 Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The NR3C2 antibody detected the NR3C2 protein (arrow).
NR3C2 Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The NR3C2 antibody detected the NR3C2 protein (arrow).

Western blot

NR3C2 Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The NR3C2 antibody detected the NR3C2 protein (arrow).
NR3C2 Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The NR3C2 antibody detected the NR3C2 protein (arrow).

Western blot

NR3C2 Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The NR3C2 antibody detected the NR3C2 protein (arrow).
NR3C2 Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The NR3C2 antibody detected the NR3C2 protein (arrow).


Requested From: 
Date Requested: 6/24/2018

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