Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 2G5] (IgG2b) to Mouse MHC Class I
Mouse, Rat, Bovine, Guinea pig, Pig, Sheep
Mouse MHC Class I
Mouse, Rat, Bovine, Guinea pig, Pig, Sheep (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [2G5]
Protein G purified
Specificity and Use
MHC Class I antibody was raised against purified H-2Kb and H-2Db MHC-I molecules.
Recognizes a monomorphic epitope on the mouse MHC class I antigen. The epitope recognized is conformation dependent and is reported to be phylogenetically conserved. Reactivity has been observed with some canine samples suggesting that this antibody may recognize a polymorphic epitope of canine MHC class 1. Species cross-reactivity: rat, guinea pig, sheep, bovine, porcine.
Suitable for use in Flow cytometry: Neat-1:5; 10 ul labels 10^6 cells in 100ul. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, pH 7.4, 1% BSA, 0.09% sodium azide
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. Sensitive to light.