Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
MGLL / Monoacylglycerol Lipase antibody was raised against synthetic peptide located between aa41-90 of rat MGLL (Q8R431, NP_612511). Percent identity by BLAST analysis: Human, Rat (100%); Rabbit, Pig (92%); Mouse, Dog, Horse, Guinea pig (85%).
MAG Lipase is a lipase that functions together with hormone-sensitive lipase to hydrolyze intracellular triglyceride stores in adipocytes and other cell types to form fatty acids and glycerol. MAG lipase also works with lipoprotein lipase to hydrolyze monoglycerides resulting from degradation of lipoprotein triglycerides. It is localized in the enteric nervous system to function in the regulation of levels of endocannabinoids, and regulates intestinal motility and has a role in digestion.