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Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.
Gene Name: | mesoderm development candidate 2 |
Synonyms: | MESDC2, BOCA, Mesoderm development protein, MESD, KIAA0081, LDLR chaperone MESD |
Target Sequences: | D42039 Q14696 Q14696 |
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